{"id":177,"date":"2019-09-03T21:12:40","date_gmt":"2019-09-04T01:12:40","guid":{"rendered":"http:\/\/www.nutriiq.ca\/wordpress\/?p=177"},"modified":"2023-05-09T12:26:24","modified_gmt":"2023-05-09T16:26:24","slug":"vitamin-b3-niacin-dietary-sources","status":"publish","type":"post","link":"https:\/\/www.nutriiq.ca\/wordpress\/vitamin-b3-niacin-dietary-sources\/","title":{"rendered":"Vitamin B3 (Niacin): Reference and Dietary Sources"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">On this page<\/p>\n<label for=\"ez-toc-cssicon-toggle-item-69e2b4dcc8f26\" class=\"ez-toc-cssicon-toggle-label\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input type=\"checkbox\"  id=\"ez-toc-cssicon-toggle-item-69e2b4dcc8f26\" checked aria-label=\"Toggle\" \/><nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.nutriiq.ca\/wordpress\/vitamin-b3-niacin-dietary-sources\/#Introduction\" >Introduction<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.nutriiq.ca\/wordpress\/vitamin-b3-niacin-dietary-sources\/#Recommended_Dietary_Allowances_RDAs_for_Niacin_Vitamin_B3\" >Recommended Dietary Allowances (RDAs) for Niacin (Vitamin B3)&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.nutriiq.ca\/wordpress\/vitamin-b3-niacin-dietary-sources\/#Food_Sources_of_Niacin\" >Food Sources of Niacin<\/a><ul class='ez-toc-list-level-4' ><li class='ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.nutriiq.ca\/wordpress\/vitamin-b3-niacin-dietary-sources\/#Selected_Food_Sources_of_Vitamin_B2\" >Selected Food Sources of Vitamin B2<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-4'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.nutriiq.ca\/wordpress\/vitamin-b3-niacin-dietary-sources\/#References\" >References<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>We identified Vitamin B3 (Niacin) dietary sources, such as  poultry, beef, and fish, provided reference values, and described testing methods, benefits, and toxicity.\u00a0Nutri-IQ recommends to Wellness Practitioners to check nutritional status with our <a href=\"https:\/\/www.nutriiq.ca\/nutriIQ.php\" target=\"_blank\" rel=\"noreferrer noopener\">Nutritional Balance Assessment Tool<\/a> in order to holistically recognize and close nutritional gaps.<\/p><\/blockquote>\n\n\n\n<h3 class=\"wp-block-heading\">Abstract<\/h3>\n\n\n\n<p>In this article, we describe:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the major purposes of this specific nutrient in the human body,&nbsp;<\/li><li>its experimentally confirmed health uses,&nbsp;<\/li><li>conventional ways to estimate nutrient status,<\/li><li>nutrient\u2019s toxicities and deficiencies,<\/li><li>experimentally confirmed and approved levels of the nutrient intake for different demographics,<\/li><li>dietary sources of the nutrient.<\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Introduction\"><\/span>Introduction<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Niacin (also known as vitamin B3) is one of the water-soluble B vitamins. Niacin is the generic name for nicotinic acid (pyridine-3-carboxylic acid), nicotinamide (niacinamide or pyridine-3-carboxamide), and related derivatives, such as nicotinamide riboside. Niacin is naturally present in many foods, added to some food products, and available as a dietary supplement.<\/p>\n\n\n\n<p>B Complex vitamins are all water soluble and are not stored very well in the body. Thus, they are needed daily through diet or supplement to support their many functions. Deficiencies of one or more of the B vitamins may occur fairly easily, especially during times of fasting or dieting for weight loss or with diets that include substantial amounts of refined and processed food, sugar, or alcohol. <\/p>\n\n\n\n<p>All tissues in the body convert absorbed niacin into its main metabolically active form, the coenzyme nicotinamide adenine dinucleotide (NAD). More than 400 enzymes require NAD to catalyze reactions in the body, which is more than for any other vitamin-derived coenzyme. NAD is also converted into another active form, the coenzyme nicotinamide adenine dinucleotide phosphate (NADP), in all tissues except skeletal muscle.<\/p>\n\n\n\n<p>B complex vitamins are fairly easily digested from food or supplements and then absorbed into the blood, mainly from the small intestine. When the amount of Bs taken exceeds the body\u2019s needs, the excess is easily excreted in the urine, giving it a dark yellow color.&nbsp;<\/p>\n\n\n\n<p>The most sensitive and reliable measure of niacin status is the urinary excretion of its two major methylated metabolites, N1-methyl-nicotinamide and N1-methyl-2-pyridone-5-carboxamide. Excretion rates in adults of more than 17.5 micromol\/day of these two metabolites reflect adequate niacin status, while excretion rates between 5.8 and 17.5 micromol\/day reflect low niacin status. An adult has deficient niacin status when urinary-excretion rates are less than 5.8 micromol\/day. Indicators of inadequacy such as this and other biochemical signs (e.g., a 2-pyridone oxidation product of N1-methyl-nicotinamide below detection limits in plasma or low erythrocyte NAD concentrations) occur well before overt clinical signs of deficiency. Another measure of niacin status takes into account the fact that NAD levels decline as niacin status deteriorates, whereas NADP levels remain relatively constant. A \u201cniacin number\u201d (NAD\/[NAD + NADP] concentrations in whole blood x 100) below 130 suggests niacin deficiency. A \u201cniacin index\u201d (the ratio of erythrocyte NAD to NADP concentrations) below 1 suggests that an individual is at risk of developing niacin deficiency. No functional biochemical tests that reflect total body stores of niacin are available.<\/p>\n\n\n\n<p>Severe niacin deficiency leads to pellagra, a disease characterized by a pigmented rash or brown discoloration on skin exposed to sunlight; the skin also develops a roughened, sunburned-like appearance. As pellagra progresses, anorexia develops, and the affected individual eventually dies. Niacin inadequacy usually arises from insufficient intakes of foods containing niacin and tryptophan. It can also be caused by factors that reduce the conversion of tryptophan to niacin, such as low intakes of other nutrients. The following groups are among those most likely to have inadequate niacin status: malnourished individuals; people with Hartnup disease; and people with carcinoid syndrome. Despite numerous claims,  experts do not agree on the value of nicotinic acid to treat cardiovascular disease, especially given its side effects, safety concerns, and poor patient compliance. <\/p>\n\n\n\n<p>No adverse effects have been reported from the consumption of naturally occurring niacin in foods. However, high intakes of both nicotinic acid and nicotinamide taken as a dietary supplement or medication can cause adverse effects, including hepatotoxicity. <\/p>\n\n\n\n<p>Assessment of nutritional balance brings<strong> cost-effective immediate answers<\/strong> when your client:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Feels stressed, tired, depressed<\/li><li>Takes prescription meds but cannot alleviate symptoms<\/li><li>Wants to achieve optimal wellness, prevent chronic disease, and manage aging process<\/li><\/ul>\n\n\n\n<p><strong><a href=\"https:\/\/www.nutriiq.ca\">Nutri-IQ<\/a>\u2122 <\/strong>is a unique tool that helps Wellness Professionals to easy and conveniently  identify clients\u2019 <strong>nutritional gaps <\/strong>as possible causes for clients\u2019 complaints.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Recommended_Dietary_Allowances_RDAs_for_Niacin_Vitamin_B3\"><\/span>Recommended Dietary Allowances (RDAs) for Niacin (Vitamin B3)&nbsp;<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table><tbody><tr><td><strong>Age<\/strong><\/td><td><strong>Male<\/strong><\/td><td><strong>Female<\/strong><\/td><td><strong>Pregnancy<\/strong><\/td><td><strong>Lactation<\/strong><\/td><\/tr><tr><td>Birth to 6 months*<\/td><td>2 mg<\/td><td>2 mg<\/td><td>&nbsp;<\/td><td>&nbsp;<\/td><\/tr><tr><td>7\u201312 months*<\/td><td>4 mg NE<\/td><td>4 mg NE<\/td><td>&nbsp;<\/td><td>&nbsp;<\/td><\/tr><tr><td>1\u20133 years<\/td><td>6 mg NE<\/td><td>6 mg NE<\/td><td>&nbsp;<\/td><td>&nbsp;<\/td><\/tr><tr><td>4\u20138 years<\/td><td>8 mg NE<\/td><td>8 mg NE<\/td><td>&nbsp;<\/td><td>&nbsp;<\/td><\/tr><tr><td>9\u201313 years<\/td><td>12 mg NE<\/td><td>12 mg NE<\/td><td>&nbsp;<\/td><td>&nbsp;<\/td><\/tr><tr><td>14\u201318 years<\/td><td>16 mg NE<\/td><td>14 mg NE<\/td><td>18 mg NE<\/td><td>17 mg NE<\/td><\/tr><tr><td>19+ years<\/td><td>16 mg NE<\/td><td>14 mg NE<\/td><td>18 mg NE<\/td><td>17 mg NE<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>* Intake at this level is assumed to ensure nutritional adequacy (Adequate Intake or AI), established when evidence is insufficient to develop an RDA.&nbsp;&nbsp;The AI for infants from birth to 6 months is for niacin alone, as young infants use almost all the protein they consume for growth and development; it is equivalent to the mean intake of niacin in healthy, breastfed infants. For infants aged 7-12 months, the AI for niacin is in mg NE and is based on amounts consumed from breast milk and solid foods.<\/li><li>The current RDAs for niacin as mg of niacin equivalents (NE). 1 NE is defined as 1 mg niacin or 60 mg of the amino acid tryptophan (which the body can convert to niacin).&nbsp;<\/li><li>Niacin RDAs for adults are based on niacin metabolite excretion data. For children and adolescents, niacin RDAs are extrapolated from adult values on the basis of body weight.<\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Food_Sources_of_Niacin\"><\/span>Food Sources of Niacin<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Niacin is present in a wide variety of foods. Many animal-based foods\u2014including poultry, beef, and fish\u2014provide about 5-10 mg niacin per serving, primarily in the highly bioavailable forms of NAD and NADP. Plant-based foods, such as nuts, legumes, and grains, provide about 2-5 mg niacin per serving, mainly as nicotinic acid. In some grain products, however, naturally present niacin is largely bound to polysaccharides and glycopeptides that make it only about 30% bioavailable. Many breads, cereals, and infant formulas in the United States and many other countries contain added niacin. Niacin that is added to enriched and fortified foods is in its free form and therefore highly bioavailable.<\/p>\n\n\n\n<p>Tryptophan is another food source of niacin because this amino acid\u2014when present in amounts beyond that required for protein synthesis\u2014can be converted to NAD, mainly in the liver. The most commonly used estimate of efficiency for tryptophan conversion to NAD is 1:60 (i.e., 1 mg niacin [NAD] from 60 mg tryptophan). Turkey is an example of a food high in tryptophan; a 3-oz portion of turkey breast meat provides about 180 mg tryptophan, which could be equivalent to 3 mg niacin. However, the efficiency of the conversion of tryptophan to NAD varies considerably in different people.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Selected_Food_Sources_of_Vitamin_B2\"><\/span>Selected Food Sources of Vitamin B2<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<figure class=\"wp-block-table is-style-stripes\"><table><thead><tr><td><strong>Food<\/strong><\/td><td><strong>Milligrams<br \/>(mg) per<br \/>serving<\/strong><\/td><td><strong>Percent<br \/>DV**<\/strong><\/td><\/tr><\/thead><tbody><tr><td>Pan fried beef liver, 3 ounces<\/td><td>14.9<\/td><td>93<\/td><\/tr><tr><td>Grilled chicken breast, 3 ounces<\/td><td>10.3<\/td><td>64<\/td><\/tr><tr><td>Canned Marinara sauce, 1 cup<\/td><td>10.3<\/td><td>64<\/td><\/tr><tr><td>Roasted turkey breast, 3 ounces<\/td><td>10.0<\/td><td>63<\/td><\/tr><tr><td>Cooked sockeye salmon, 3 ounces<\/td><td>8.6<\/td><td>54<\/td><\/tr><tr><td>Canned in water tuna, 3 ounces<\/td><td>8.6<\/td><td>54<\/td><\/tr><tr><td>Pork tenderloin, roasted, 3 ounces<\/td><td>6.3<\/td><td>39<\/td><\/tr><tr><td>Beef, ground, 90% lean, pan-browned, 3 ounces<\/td><td>5.8<\/td><td>36<\/td><\/tr><tr><td>Brown rice, cooked, 1 cup<\/td><td>5.2<\/td><td>33<\/td><\/tr><tr><td>Fortified breakfast cereal<\/td><td>5.0<\/td><td>31<\/td><\/tr><tr><td>Dry roasted peanuts, 1 ounce<\/td><td>4.2<\/td><td>26<\/td><\/tr><tr><td>White enriched rice, cooked, 1 cup<\/td><td>2.3<\/td><td>14<\/td><\/tr><tr><td>Baked russet potato (russet), 1 medium<\/td><td>2.3<\/td><td>14<\/td><\/tr><tr><td>Dry roasted sunflower seeds, 1 ounce<\/td><td>2.0<\/td><td>13<\/td><\/tr><tr><td>Whole wheat bread, 1 slice<\/td><td>1.4<\/td><td>8<\/td><\/tr><tr><td>Dry roasted pumpkin seeds, 1 ounce<\/td><td>1.3<\/td><td>8<\/td><\/tr><tr><td>Soymilk, unfortified, 1 cup<\/td><td>1.3<\/td><td>8<\/td><\/tr><tr><td>White enriched bread, 1 slice<\/td><td>1.3<\/td><td>8<\/td><\/tr><tr><td>Lentils, boiled and drained, \u00bd cup<\/td><td>1.0<\/td><td>6<\/td><\/tr><tr><td>Bulgur, cooked, 1 cup<\/td><td>0.9<\/td><td>6<\/td><\/tr><tr><td>Banana, 1 medium<\/td><td>0.8<\/td><td>5<\/td><\/tr><tr><td>Cooked edamame, \u00bd cup<\/td><td>0.7<\/td><td>4<\/td><\/tr><tr><td>Raisins, \u00bd cup<\/td><td>0.6<\/td><td>4<\/td><\/tr><tr><td>Cherry tomatoes, \u00bd cup<\/td><td>0.5<\/td><td>3<\/td><\/tr><tr><td>Cooked broccoli, \u00bd cup<\/td><td>0.4<\/td><td>3<\/td><\/tr><tr><td>Dry roasted cashews, 1 ounce<\/td><td>0.4<\/td><td>3<\/td><\/tr><tr><td>Plain yogurt, 1 cup<\/td><td>0.3<\/td><td>2<\/td><\/tr><tr><td>Apple, 1 medium<\/td><td>0.2<\/td><td>1<\/td><\/tr><tr><td>Canned chickpeas, drained, 1 cup<\/td><td>0.2<\/td><td>1<\/td><\/tr><tr><td>Milk, 1 cup<\/td><td>0.2<\/td><td>1<\/td><\/tr><tr><td>Boiled spinach, \u00bd cup<\/td><td>0.2<\/td><td>1<\/td><\/tr><tr><td>Firm tofu, raw, \u00bd cup<\/td><td>0.2<\/td><td>1<\/td><\/tr><tr><td>Chopped onions, \u00bd cup<\/td><td>0.1<\/td><td>1<\/td><\/tr><tr><td>Egg, large<\/td><td>0<\/td><td>0<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>*DV = Daily Value.<\/li><li>The DV for niacin is used as the basis for the values the table above is 16 mg for adults and children age 4 and older. <\/li><li>Foods providing 20% or more of the DV are considered to be high sources of a nutrient, but foods providing lower percentages of the DV also contribute to a healthful diet.<\/li><\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"References\"><\/span>References<span class=\"ez-toc-section-end\"><\/span><\/h4>\n\n\n\n<ul class=\"wp-block-list\"><li>Elson Haas. \u201cStaying Healthy with Nutrition\u201d<\/li><li>U.S. Department of Health &amp; Human Services:&nbsp;<a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\">https:\/\/<\/a><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\" target=\"_blank\" rel=\"noreferrer noopener\">ods.od.nih.gov<\/a><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\">\/factsheets\/Niacin-<\/a><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\" target=\"_blank\" rel=\"noreferrer noopener\">HealthProfessional<\/a><a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Niacin-HealthProfessional\/\">\/<\/a><\/li><\/ul>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Niacin is present in a wide variety of foods. Many animal-based foods\u2014including poultry, beef, and fish\u2014provide about 5-10 mg niacin per serving, primarily in the highly bioavailable forms of NAD and NADP. Plant-based foods, such as nuts, legumes, and grains, provide about 2-5 mg niacin per serving, mainly as nicotinic acid.<\/p>\n","protected":false},"author":1,"featured_media":180,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"colormag_page_container_layout":"default_layout","colormag_page_sidebar_layout":"default_layout","_lmt_disableupdate":"no","_lmt_disable":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[29],"tags":[33,17,39,62,63,61,64],"class_list":["post-177","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-vitamins","tag-dietary-sources","tag-dietary-sources-of-b-vitamins","tag-dietary-sources-of-vitamin-b3","tag-niacin-deficiency","tag-niacin-toxicity","tag-vitamin-b3-deficiency","tag-vitamin-b3-toxicity"],"aioseo_notices":[],"modified_by":"admin","_links":{"self":[{"href":"https:\/\/www.nutriiq.ca\/wordpress\/wp-json\/wp\/v2\/posts\/177","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nutriiq.ca\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nutriiq.ca\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nutriiq.ca\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nutriiq.ca\/wordpress\/wp-json\/wp\/v2\/comments?post=177"}],"version-history":[{"count":0,"href":"https:\/\/www.nutriiq.ca\/wordpress\/wp-json\/wp\/v2\/posts\/177\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.nutriiq.ca\/wordpress\/wp-json\/wp\/v2\/media\/180"}],"wp:attachment":[{"href":"https:\/\/www.nutriiq.ca\/wordpress\/wp-json\/wp\/v2\/media?parent=177"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nutriiq.ca\/wordpress\/wp-json\/wp\/v2\/categories?post=177"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nutriiq.ca\/wordpress\/wp-json\/wp\/v2\/tags?post=177"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}